Avisco Ltd. World leader in Inula viscosa research production applications and products

INULA VISOCSA EXTRACT Topical treatment

Clinically tested as a topical application on people diagnosed as suffering from Osteoarthritis also found by users effective as a topical treatment that relieves  backpain and muscle pain 
Of the shelf topical product

Roll-on head for economical topical application of a un

Content: 10 ml
Ingredients 10% inula viscosa ethyl acetate extract, food grade emulsifiers, edible vegetable oil, water

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Detailed Description

Inula viscosa is a medicinal plant growing in the wild in the Mediterranean basin, it has a recorded use in traditional medicine that spans over 2000 years, in modern times Inula viscosa and its medicinal virtues were a subject of over 50 scientific studies, some of the uses in traditional medicine is pain relief and treatment of open wounds, one of the interesting uses in traditional medicine was treatment of joints pain with fresh leaves of Inula viscosa, taking this clue from traditional medicine, we have committed a pilot clinical study on people who were Doctor diagnosed as suffering form Osteoarthritis in their hands,  the people in the study applied to the top of their hands inula viscose extract to their hands, this topical treatment reduced the pain, reduced the swelling, increase their fingers range of motion and strength, after 28 days of inula viscosa extract application all the study participants were free of Osteoarthritis symptoms.

Following the clinical study (in the USA) prof of Inula viscosa extract performance Vs Osteoarthritis, we have developed the product called Inula Arthritis, it is a 10 ml vial with a roll-on dead that is good for a month topical application.  People used this product to relief back-pain, muscle pain, stiff neck pain and treatment of open wounds, now I am preparing for industrial scale cultivation of Inula viscosa extract production FDA approval and commercialization.

10 ml of Inula viscosa Ethyl Acetate extract in waterborne emulsion11% Inula viscosa extract packaged in a glass vial with roll on head that helps even this layer topical application, good for a month daily application.

Clinically tested an effective in pain relief, swelling reduction, and increased strength and range of motion, tested on people diagnosed as suffering from Osteoarthritis in their hands, it is analgesic, reduces back-pain aches knee aches


🌍 Global Prevalence of Osteoarthritis

·              Total affected (2021): Approximately 607 million people, or 7.7% of the global population.

·              Most commonly affected joint: The knee is the most prevalent site of OA.


👵 Age Segmentation

·              General trend: OA prevalence increases significantly with age.

·              Key age groups:

o       The greatest increase in incidence occurs between ages 35–44, especially in the 35–39 and 40–44 brackets.

o       OA is most common in older adults, particularly those over 60, due to cumulative joint wear and metabolic changes.


🚻 Gender Segmentation

·              Women are disproportionately affected:

o       In 2021, the age-standardized prevalence among females was 8,034 per 100,000, compared to 5,763 per 100,000 for males.

o       This gap is expected to narrow slightly by 2036, but women will still have higher prevalence rates.

·              Reasons for disparity:

o       Hormonal changes post-menopause

o       Higher rates of obesity and metabolic risk factors in women

o       Differences in joint biomechanics and occupational exposure


📈 Regional and Socioeconomic Factors

·              High-income regions (e.g., Asia Pacific) show higher prevalence rates—up to 8,608 per 100,000.

·              Areas with higher socio-demographic index (SDI) tend to have greater incidence and disability burden from OA.


📊 Age & Gender Prevalence of Osteoarthritis

1. Global Burden and Age Distribution

·              This chart from the Osteoarthritis Action Alliance shows how OA prevalence increases sharply with age, especially after 45, and highlights the gender gap.

2. Joint-Specific OA by Age and Gender

·              The Annals of the Rheumatic Diseases provides a breakdown of OA incidence in the knee, hip, and hand, showing higher rates in women across all age groups.

3. Why Women Are at Higher Risk

·              This visual from Hospital for Special Surgery explains hormonal and biomechanical factors contributing to higher OA risk in women.

4. CDC Data on Arthritis by Age and Sex

·              The CDC chart shows arthritis prevalence by age group and sex in the U.S., with women consistently showing higher rates across all age brackets.

Here’s a comprehensive overview of the current treatments for osteoarthritis (OA), based on the latest medical guidance:


💊 Medications

Type

Examples

Purpose

Notes

Analgesics

Acetaminophen, Tramadol

Relieve pain

Acetaminophen is for mild pain; Tramadol is prescription-only and may carry addiction risk

NSAIDs

Ibuprofen, Naproxen, Celecoxib

Reduce pain & inflammation

Available OTC or by prescription; topical forms (gels/creams) have fewer side effects

Duloxetine

Cymbalta

Treat chronic pain

Originally an antidepressant, now approved for OA pain

Opioids

Hydrocodone, Oxycodone

Severe pain relief

Used sparingly due to addiction risk

Corticosteroids

Prednisone, Cortisone injections

Reduce inflammation

Injections offer temporary relief; limited to a few per year


🧘‍♀️ Non-Drug Therapies

·              Physical Therapy: Strengthens muscles around joints, improves flexibility, reduces pain.

·              Occupational Therapy: Helps adapt daily tasks to reduce joint strain.

·              Exercise: Low-impact activities like swimming, walking, biking, and yoga are highly beneficial.

·              Weight Loss: Reduces joint pressure—losing 10% of body weight can significantly improve symptoms.


🧴 Topical & Injectable Options

·              Topical NSAIDs: Gels like diclofenac applied directly to joints.

·              Counterirritants: Creams with menthol or capsaicin to block pain signals.

·              Steroid Injections: Provide short-term relief for severe inflammation.

·              Hyaluronic Acid Injections: Lubricate joints, though effectiveness varies.


🌿 Alternative & Lifestyle Approaches

·              Supplements: Glucosamine and chondroitin—evidence is mixed on effectiveness.

·              Diet: Anti-inflammatory foods (e.g., omega-3s, leafy greens) may help.

·              Mind-body therapies: Meditation, acupuncture, and tai chi can support pain management.


🏥 Surgical Options

·              Joint Replacement (e.g., knee or hip): Considered when other treatments fail.

·              Arthroscopy or Osteotomy: Less common; used in specific cases.

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